Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.400 Biomarker PSYGENET To test this hypothesis, we examined protein expression of excitatory amino acid transporter 1-3 and vesicular glutamate transporter 1 and 2 in subjects with schizophrenia (n=23) and a comparison group (n=27). 23356950

2013
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.400 Biomarker PSYGENET Our data may be important for a better understanding of the contribution of reduced VGLUT1-mediated presynaptic glutamatergic neurotransmission in the generation of several behavioural abnormalities associated with schizophrenia. 22197296

2012
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.400 Biomarker PSYGENET No significant changes in complexin 1, VGAT, complexin 2, VGluT1, dysbindin, NAV2, or VAMP1 mRNA expression were found; however, expression of mRNAs associated with plasticity/cytoskeletal modification (GAP43 and NAV1) was reduced in schizophrenia. 21145444

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.400 Biomarker PSYGENET The VGluT1 mRNA/VGAT mRNA ratio was unchanged in schizophrenia, as was the ratio of complexin 2 mRNA to complexin 1 mRNA (related to synaptic vesicle fusion in excitatory and inhibitory terminals, respectively). 21396926

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.310 Biomarker PSYGENET Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factors. 22707231

2012
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.310 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.310 Biomarker PSYGENET Increased VGluT1 expression is supportive of elevated glutamate neurotransmission in the anterior cingulate cortex in bipolar disorder. 20079890

2010
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.310 Biomarker PSYGENET We also found a negative correlation between age and VGLUT1 mRNA expression in BD in the ERC and ITG. 19839996

2009
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.310 Biomarker PSYGENET Increased vulnerability to depressive-like behavior of mice with decreased expression of VGLUT1. 19409534

2009
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0023186
Disease: Learning Disorders
Learning Disorders 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0025261
Disease: Memory Disorders
Memory Disorders 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751262
Disease: Adult Learning Disorders
Adult Learning Disorders 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751263
Disease: Learning Disturbance
Learning Disturbance 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751265
Disease: Learning Disabilities
Learning Disabilities 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751292
Disease: Age-Related Memory Disorders
Age-Related Memory Disorders 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751293
Disease: Memory Disorder, Semantic
Memory Disorder, Semantic 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751294
Disease: Memory Disorder, Spatial
Memory Disorder, Spatial 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0751295
Disease: Memory Loss
Memory Loss 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C1330966
Disease: Developmental Academic Disorder
Developmental Academic Disorder 		0.300 Biomarker CTD_human Expression of VGLUTs contributes to degeneration and acquisition of learning and memory. 21295146

2011
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0022333
Disease: Jacksonian Seizure
Jacksonian Seizure 		0.300 Biomarker CTD_human Hyperthermic seizure induces persistent alteration in excitability of the dentate gyrus in immature rats. 18495095

2008
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0036572
Disease: Seizures
Seizures 		0.300 Biomarker CTD_human Ten-twelve weeks after hyperthermic seizure, animals (approximately 68%) showed electroencephalographic seizure activity with increased VGLUT-1 immunoreactivity in the dentate gyrus. 18495095

2008
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures 		0.300 Biomarker CTD_human Hyperthermic seizure induces persistent alteration in excitability of the dentate gyrus in immature rats. 18495095

2008
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0234533
Disease: Generalized seizures
Generalized seizures 		0.300 Biomarker CTD_human Hyperthermic seizure induces persistent alteration in excitability of the dentate gyrus in immature rats. 18495095

2008
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures 		0.300 Biomarker CTD_human Hyperthermic seizure induces persistent alteration in excitability of the dentate gyrus in immature rats. 18495095

2008
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.300 Biomarker CTD_human Hyperthermic seizure induces persistent alteration in excitability of the dentate gyrus in immature rats. 18495095

2008