Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 58533
Gene Symbol: SNX6
SNX6
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease
0.010 Biomarker BEFREE SNX6 is a transient subunit of the retromer, an endosome-Golgi retrieval complex whose Vps35 subunit is strongly associated with PD. 30640902

2019

Entrez Id: 58533
Gene Symbol: SNX6
SNX6
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.010 AlteredExpression BEFREE These results indicate that Pb exposure can reduce the expression of SNX6 and lead to a decrease in Homer1 expression, which affects the changes in dendritic spines causing learning and memory impairment. 30738087

2019

Entrez Id: 58533
Gene Symbol: SNX6
SNX6
CUI: C0542476
Disease: Forgetful
Forgetful
0.010 AlteredExpression BEFREE These results indicate that Pb exposure can reduce the expression of SNX6 and lead to a decrease in Homer1 expression, which affects the changes in dendritic spines causing learning and memory impairment. 30738087

2019

Entrez Id: 58533
Gene Symbol: SNX6
SNX6
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 AlteredExpression BEFREE In vitro studies demonstrated that silencing of SNX6 expression reduced cell proliferation, colony formation, invasion, and metastasis. 30307473

2018

Entrez Id: 58533
Gene Symbol: SNX6
SNX6
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.010 Biomarker BEFREE In the present study, by using the Cancer Genome Atlas (TCGA) dataset analysis, we demonstrated that sorting nexin 6 (SNX6) serves as a biomarker for predicting prognosis of pancreatic cancer. 30307473

2018

Entrez Id: 58533
Gene Symbol: SNX6
SNX6
CUI: C0346647
Disease: Malignant neoplasm of pancreas
Malignant neoplasm of pancreas
0.010 Biomarker BEFREE In the present study, by using the Cancer Genome Atlas (TCGA) dataset analysis, we demonstrated that sorting nexin 6 (SNX6) serves as a biomarker for predicting prognosis of pancreatic cancer. 30307473

2018