Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.500 Biomarker CTD_human Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. 20639879

2010
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.500 SusceptibilityMutation ORPHANET

Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. 30423114

2019
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes. 31407831

2019
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation BEFREE However, we did not find significant association between neither BANK1 rs3733197 polymorphism nor MMEL1/TNFRSF14 rs3890745 polymorphism and RA. 28925718

2017
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis. 26546613

2016
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. 24532676

2015
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. 24449572

2014
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASDB Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. 24449572

2014
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation BEFREE A series of bioinformatic analyses identified TNFRSF14-MMEL1 at the 1p36 locus and IKZF3-ORMDL3-GSDMB at the 17q12 locus as the genes most likely associated with RA. 22365150

2012
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation BEFREE We also demonstrate that in the presence of SE, the minor allele of MMEL1-TNFRSF14 significantly reduces RA risk in a dominant manner, whereas TRAF1-C5 increases the risk. 21614018

2011
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 Biomarker BEFREE This study identifies MMEL1 and CTLA4 as RA susceptibility genes, provides suggestive evidence of association for a further six loci in the Han Chinese population and confirms lack of PTPN22 association in Asian populations. 21784728

2011
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASCAT Common variants at CD40 and other loci confer risk of rheumatoid arthritis. 18794853

2008
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.440 GeneticVariation GWASDB Common variants at CD40 and other loci confer risk of rheumatoid arthritis. 18794853

2008
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0023892
Disease: Biliary cirrhosis
Biliary cirrhosis 		0.400 Biomarker CTD_human Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. 20639879

2010
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0023892
Disease: Biliary cirrhosis
Biliary cirrhosis 		0.400 Biomarker HPO

Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0238065
Disease: Secondary Biliary Cholangitis
Secondary Biliary Cholangitis 		0.300 Biomarker CTD_human Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. 20639879

2010
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C4551595
Disease: Biliary Cirrhosis, Primary, 1
Biliary Cirrhosis, Primary, 1 		0.300 Biomarker CTD_human Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. 20639879

2010
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.120 GeneticVariation BEFREE Two multiple sclerosis (MS)-associated genetic regions were modeled; DRB1 (a Class II molecule of the major histocompatibility complex) and MMEL1 (an endopeptidase that degrades both neuropeptides and β-amyloid). 24727690

2014
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.120 GeneticVariation GWASCAT Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602

2013
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.120 GeneticVariation GWASDB Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. 22190364

2011
Entrez Id: 79258
Gene Symbol: MMEL1
MMEL1
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.120 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088

2011