Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 AlteredExpression BEFREE Finally, higher levels of CSF YKL-40, ICAM-1, and Flt-1 increased risk of development of AD dementia in patients without dementia. 30054439

2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 AlteredExpression BEFREE Changes in CD200 and ICAM-1 levels did not correlate with LB pathology, but with AD pathology. 28390825

2017
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 Biomarker BEFREE A positive correlation was observed between IL-18 and ICAM-1 in AD patients, whereas a negative correlation was evident in the HC group. 22272623

2012
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation BEFREE The current study does not demonstrate an association between CD14 (-260) polymorphism and AD, neither through an independent effect nor through interaction with APOE epsilon4 allele or interleukin (IL)-1A, IL-6, IL-8, tumor necrosis factor (TNF)-alpha, and intercellular adhesion molecule-1 polymorphisms. 15854776

2005
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation LHGDN Our study in the Spanish population argues against the hypothesis that polymorphism at codon 469 of the ICAM-1 gene is causally related to AD. 15048650

2004
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation BEFREE Our study in the Spanish population argues against the hypothesis that polymorphism at codon 469 of the ICAM-1 gene is causally related to AD. 15048650

2004
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation BEFREE We therefore conclude that the E469K polymorphism of ICAM1 is not a risk factor for AD or PD. 12524171

2003
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation BEFREE This study shows for the first time an association between ICAM-1 E/K gene polymorphism and AD, suggesting that polymorphisms of the ICAM-1 gene may be clinically important and confirming that inflammatory mechanisms may be crucial in the pathophysiology of neuro-degenerative diseases. 12498973

2003