Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0003864
Disease: Arthritis
Arthritis 		0.020 Biomarker BEFREE Production of pro-inflammatory cytokines is reduced by ex vivo gene-silencing of miR-34a. miR-34a-deficient mice are resistant to collagen-induced arthritis and interaction of DCs and T cells from these mice are reduced and do not support the development of Th17 cells in vivo. 28639625

2017
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
CUI: C0003864
Disease: Arthritis
Arthritis 		0.020 Biomarker BEFREE Arthritis scores decreased and joint swelling was alleviated with the miR-34a antagomir treatment and the expression of inflammatory cytokines was decreased. miR-34a antagomir delivery significantly decreased the percentage of T cells present including T helper (Th) 1, Th2, Th17 and regulatory T cells. 28810629

2017