Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 Biomarker BEFREE Quantitative real-time polymerase chain reaction analysis, western blot analysis and immunohistochemistry were used to quantify renin, ACE, angiotensin type 1 and type 2 receptors, VEGF and MMP-13 in OA and RA. 31785770

2020

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 Biomarker BEFREE Primary prevention of myocardial infarction with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in hypertensive patients with rheumatoid arthritis-A nationwide cohort study. 29216228

2017

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 Biomarker BEFREE Heritability of RA was estimated as 62.2% and 56.1% in the AE and ACE models, respectively. 26727555

2016

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 GeneticVariation BEFREE Our meta-analysis demonstrates that the ACE I/D polymorphism is associated with susceptibility to RA, especially in Arab populations. 23413281

2015

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 GeneticVariation BEFREE Our study suggests that high frequency of the ACE D allele contributes to the heritability of RA susceptibility compared to other ACE alleles. 23981749

2013

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 GeneticVariation BEFREE As a result of our study, angiotensin converting enzyme gene I/D polymorphism DD genotype could be a genetic marker in rheumatoid arthritis in the Turkish study population. 23000565

2012

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 Biomarker BEFREE Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1, and ACE genes with rheumatoid arthritis in South Asians and Caucasians of East Midlands in the United Kingdom. 20401725

2011

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 GeneticVariation BEFREE Our study found an association between ACE deletion polymorphism and RA. 17985406

2007

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.090 GeneticVariation BEFREE Gene and genotype frequencies for the ACE-I/D polymorphism did not differ between those with early active severe and non-severe RA. 11036822

2000