Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.060 Biomarker BEFREE The high-sensitive C-reactive protein, α-1-acid glycoprotein, and haptoglobin increased in acute phase proteins in rheumatoid arthritis disease. 28894708

2017

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.060 AlteredExpression BEFREE Specifically, decreases in RA disease activity over time were associated with increases in PON-1 activity and levels of HDL-associated Apo A-I, and decreases in the HDL inflammatory index and levels of MPO and HDL-associated Hp. 27483410

2017

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.060 GeneticVariation BEFREE High serum levels of HP at baseline are associated with inadequate response of 12 weeks MTX treatment in recent-onset RA patients. 24863583

2016

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.060 Biomarker BEFREE They further suggest that a specific Hp fragment might be applied as a novel biomarker for the diagnosis and prognosis of inflammatory diseases such as RA. 23701120

2013

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.060 Biomarker BEFREE In vitro stimulation with the HA307-319 peptide increased the percentage of BV14S1 transcripts in PBMC from RA patients (+ 1.5 +/- 0.4%, p < 0.005) but not controls (+ 0.3 +/- 0.2%, ns), and the difference between RA patients and controls was significant (p = 0.03). 9506881

1998

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.060 Biomarker BEFREE Haptoglobin groups and rheumatoid arthritis. 4029960

1985