Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASCAT Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. 30423114

2019
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASCAT High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. 24532676

2015
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASCAT Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342

2014
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation BEFREE HLA-C rs12212594 T/C, JAM2 rs2829866 A/T and REL rs702873 G/A polymorphisms were not associated with the risk of RA. 24566686

2014
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342

2014
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation BEFREE The minor allele of REL had opposing effects upon susceptibility to disease in patients with psoriasis and RA. 23106574

2013
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation BEFREE The rs13017599 polymorphism is known to associate with rheumatoid arthritis (RA), and another SNP near REL (rs702873) was recently implicated in PsV susceptibility. 22170493

2012
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation BEFREE The REL gene, a key modulator of the NFκB pathway, is associated with PsA but the allele conferring risk to RA is protective in PsA suggesting that there are fundamental differences in the aetiological mechanisms underlying these two types of inflammatory arthritis. 22328738

2012
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASDB Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 Biomarker BEFREE In particular, recent discoveries highlight the importance of the CD40/NF-kappaB signaling pathway in RA, based on genetic association with several genes relevant to this pathway, including CD40, TRAF1, TNFAIP3, and REL. 20192992

2010
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASCAT Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 Biomarker CTD_human Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation BEFREE REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088

2009
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 Biomarker CTD_human REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088

2009
Entrez Id: 5966
Gene Symbol: REL
REL
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.460 GeneticVariation GWASDB REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088

2009