Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 Biomarker BEFREE We studied 393 patients with rheumatic diseases, including ankylosing spondylitis (ASP, n = 90), rheumatoid arthritis (RA; n = 120), psoriatic arthritis (PA, n = 126), and other disorders (n = 57). 29735171

2018
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 Biomarker BEFREE Serum complement C3 strongly correlates with whole-body insulin sensitivity in rheumatoid arthritis. 27908300

2017
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 Biomarker BEFREE Our results provide preliminary evidence for a potential role of complement C3 as a surrogate biomarker of NAFLD in RA patients. 28796299

2017
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 GeneticVariation BEFREE The protective genotype, present in 41% of controls, was less frequent in RA patients: 33% in the first sample, 24% in the ASP RA sample, and 11% in the linkage-derived subgroup. 14872483

2004
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 Biomarker BEFREE We have found low CR1 on erythrocytes in patients with rheumatoid arthritis (RA) in an Indian population. 7897264

1994
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 Biomarker BEFREE Genes associated with rheumatoid arthritis and mild inflammatory arthritis. II. Association of HLA with complement C3 and immunoglobulin Gm allotypes. 2111124

1990
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 GeneticVariation BEFREE Properdin factor B (Bf) and complement C3 polymorphisms were studied in 225 unrelated rheumatoid arthritis (RA) patients from North-East England. 3495479

1987
Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.080 Biomarker BEFREE The mean number of CR1 sites in SLE (1150/cell) but not RA (1460/cell) was significantly lower (P less than 0.01) than normal (2200/cell). 2937582

1986