Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 738
Gene Symbol: VPS51
VPS51
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 AlteredExpression BEFREE TS-RDN might reduce the expression of VEGF, Ang-2, and Tie-2 in the synovium, thus inhibiting synovial angiogenesis and playing a therapeutic role in RA. 26947206

2016

Entrez Id: 738
Gene Symbol: VPS51
VPS51
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 AlteredExpression BEFREE To determine the cellular targets of Ang signalling in RA synovial tissue, and the effects of Ang-2 neutralisation in murine collagen-induced arthritis (CIA). 22730375

2012

Entrez Id: 738
Gene Symbol: VPS51
VPS51
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 AlteredExpression BEFREE Ang2 mRNA and protein expression was observed in early psoriatic arthritis (PsA) and rheumatoid arthritis (RA) SM. 12563678

2003

Entrez Id: 738
Gene Symbol: VPS51
VPS51
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 AlteredExpression BEFREE Ang-1 was the most highly expressed ligand in late stage RA synovial fibroblasts; however, in chronic inflamed synovial tissue, Ang-2 was predominant and was expressed at strikingly high levels (70 to 120-fold increase). 11838839

2002

Entrez Id: 738
Gene Symbol: VPS51
VPS51
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 AlteredExpression BEFREE The expression pattern of Ang-2 in synovial tissue was similar in RA and OA, whereas the Ang-2 expression was low in normal tissue. 12010571

2002