Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 283120
Gene Symbol: H19
H19
CUI: C0004096
Disease: Asthma
Asthma
0.040 Biomarker BEFREE Increased ASM mass, primarily due to ASM hyperplasia, has been recognized as a hallmark of airway remodeling in asthma. 31649532

2019

Entrez Id: 283120
Gene Symbol: H19
H19
CUI: C0004096
Disease: Asthma
Asthma
0.040 Biomarker BEFREE Our results also show that A20 expression was significantly reduced in blood leukocytes and ASM obtained from patients with asthma compared to cells obtained from healthy subjects which was restored after incubation with IRL201104 in vitro, when added alone, or in combination with LPS or TNF-α in ASM. 31845415

2019

Entrez Id: 283120
Gene Symbol: H19
H19
CUI: C0004096
Disease: Asthma
Asthma
0.040 Biomarker BEFREE Together, our study provides the first in vitro evidence highlighting the antiproliferative and antimigratory roles of miR-638 in human ASMC remodeling and suggests that targeted overexpression of miR-638 in ASMCs may provide a novel therapeutic strategy for preventing ASM hyperplasia associated with asthma. 30076719

2018

Entrez Id: 283120
Gene Symbol: H19
H19
CUI: C0004096
Disease: Asthma
Asthma
0.040 Biomarker BEFREE Nrf2 reduction may underlie compromised antioxidant protection and aberrant ASM function in asthma. 21799075

2011