Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 Biomarker BEFREE More recently, microRNAs such as miR-9, miR-21, and miR-126 have been implicated for corticosteroid insensitivity in asthma and COPD. 31078066

2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 Biomarker BEFREE Moreover miR-21-5p was negatively associated with symptomatic asthma and positively associated with positive bronchodilation without symptoms. 31703106

2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 Biomarker BEFREE Association between both markers and FEV1 points to their role in determining asthma outcome following ICS treatment. miR-21 and miR-146a play a role in eosinophilic endotypic classification of asthma. 29635981

2018
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 Biomarker BEFREE We investigated the effects of an miR-21 antagomir and its mechanism of action in a mouse model of acute bronchial asthma. 28379062

2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 Biomarker BEFREE This study suggested that serum miRNA-21 is stable and detectable in serum of asthmatic children, which could promise potential biomarker in diagnosis as well as in response to therapy of asthma. 26874829

2016
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 AlteredExpression BEFREE MiR-21 modulates human airway smooth muscle cell proliferation and migration in asthma through regulation of PTEN expression. 26651881

2015
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
CUI: C0004096
Disease: Asthma
Asthma 		0.070 Biomarker BEFREE Expression of selected miRNAs, specifically let-7a, miR-21 and miR-223, that were shown to have important roles in asthma pathogenesis, were analyzed in bronchial biopsies of 24 patients with asthma, 12 mild and 12 severe, and 10 controls with no chronic disease. 25130484

2014