Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0004096
Disease: Asthma
Asthma 		0.020 Biomarker BEFREE These effects occurred independent of significant AChE inhibition in cerebellum, blood, trachealis, or isolated airway, suggesting that AChE independent OP-induced airway hyperreactivity is a cross-species phenomenon. 29939342

2018
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0004096
Disease: Asthma
Asthma 		0.020 AlteredExpression BEFREE We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of functional loss of inhibitory M2 muscarinic receptors on parasympathetic nerves. 23377347

2013