Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64375
Gene Symbol: IKZF4
IKZF4
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.030 Biomarker BEFREE Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity. 31296356

2019
Entrez Id: 64375
Gene Symbol: IKZF4
IKZF4
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.030 GeneticVariation BEFREE Both INS and IKZF4 polymorphisms modified the probability of IAA positivity at time of T1D onset but the inverse association of IKZF4 risk allele with IAA suggests that the IKZF4 polymorphism is involved in a pathway of β-cell autoimmunity alternate to the route characterized by IAA and development of T1D in early childhood. 23721563

2013
Entrez Id: 64375
Gene Symbol: IKZF4
IKZF4
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.030 GeneticVariation BEFREE Further investigation is warranted for the genetic effect marked by rs10272724, its impact on IKZF1, and the role of Ikaros and other family members, Ailios (IKZF3) and Eos (IKZF4), in autoimmunity. 21270240

2011