Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.030 Biomarker BEFREE Notably inhibitors of ADAM17 are being developed for the treatment of various autoimmune diseases. 25386842

2015
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.030 Biomarker BEFREE This review will explore the latest research on the influence of ADAM17 on the progression of inflammatory processes linked to autoimmunity and its role as modulator of inflammation. 25171914

2014
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.030 AlteredExpression BEFREE TACE RNA knockdown, the use of anti-VEGF-A monoclonal antibody and the inhibition of NF-κB activity significantly abrogated the release of pro-angiogenic factors, demonstrating that VEGF-A/TACE/VEGFR2/NF-κB axis dysfunction may be contributory to pathogenesis and exacerbation of this autoimmune condition. 22513453

2012