Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.330 Biomarker BEFREE Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a protein implicated in the control of inflammation in a number of autoimmune diseases. 28696822

2017
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.330 Biomarker CTD_human Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in mice. 25055964

2014
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.330 AlteredExpression BEFREE Specifically, decreased TIMP1 gene expression in the autoimmunity signature suggests increased MMP activity in target tissues as a result of the lack of feedback mechanism. 15373920

2004
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.330 AlteredExpression BEFREE In scleroderma (systemic sclerosis, SSc), an autoimmune disorder in which excessive extracellular matrix is deposited in skin and internal organs, one of the suggested contributory factors to the development of fibrosis is a decrease in collagenase activity that may be related to levels of serum tissue inhibitors of metalloproteinases 1 (TIMP-1). 9036925

1997