Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 84888
Gene Symbol: SPPL2A
SPPL2A
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.030 Biomarker BEFREE Thus, we believe that SPPL2a represents an interesting and druggable pharmacological target, potentially providing a novel approach for the treatment of autoimmune diseases by targeting B cells and dendritic cells. 29359565

2018

Entrez Id: 84888
Gene Symbol: SPPL2A
SPPL2A
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.030 Biomarker BEFREE The intramembrane protease signal peptide peptidase-like 2a (SPPL2a) is a potential drug target for the treatment of autoimmune diseases due to an essential role in B cells and dendritic cells. 28731783

2017

Entrez Id: 84888
Gene Symbol: SPPL2A
SPPL2A
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.030 Biomarker BEFREE Nevertheless, inhibition of SPPL2a has been suggested as novel approach to target B cells for treating autoimmunity. 25035924

2014