Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.030 Biomarker BEFREE Both groups of molecules are inhibitors of heparanase and in addition pose a low bleeding tendency. 31398734

2019

Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.030 Biomarker BEFREE Peptides derived from TFPI-2 inhibitory site were shown to reduce coagulation activation induced by heparanase and to attenuate sepsis severity and tumor growth in a mouse model, without predisposing to significant bleeding tendency. 27067977

2016

Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.030 Biomarker BEFREE The newly identified peptides potentially attenuate activation of the coagulation system induced by heparanase or LPS without predisposing to significant bleeding tendency. 25030319

2014