Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10406
Gene Symbol: WFDC2
WFDC2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker BEFREE Defining precisely the normal range of HE4 protein is crucial for the proper interpretation of tumor marker results and for a more efficient diagnosis of ovarian malignancy. 31583027

2019

Entrez Id: 10406
Gene Symbol: WFDC2
WFDC2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 Biomarker BEFREE We postulate that increased WFDC2 expression plays an important role in altering the estrogen pathway in ovarian cancer, and the identification of WFDC2 as a new player in endocrine-related cancer encourages further studies on the significance of this gene in cancer development and therapy. 26928556

2016

Entrez Id: 10406
Gene Symbol: WFDC2
WFDC2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.030 PosttranslationalModification BEFREE A novel cancer-specific DMR in the WFDC2 promoter showed frequent methylation in cancer (17/22 tissues, 6/6 cell lines), but not in the benign tissues (0/10) and normal PrEC cells. 21724842

2011