Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE This is an exploratory study to assess the impact of 3 cancer-related long non-coding RNAs (lncRNAs) (H19, MALAT1 and GA5) in blood plasma of patients with BC in predicting the response to NAC. 31640083

2020

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Hyperexpression of MALAT1 has been observed in many malignant tumors, including hepatocellular carcinoma (HCC). 31466138

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Not only cancer: the long non-coding RNA MALAT1 affects the repertoire of alternatively spliced transcripts and circular RNAs in multiple sclerosis. 30566690

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE The results confirmed that the cancer prevention effects triggered by restored ABI3BP and depleted MALAT1 as evidenced by suppressed cell growth and enhanced cell senescence. 31174563

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Interaction of lncRNA-MALAT1 and miR-124 regulates HBx-induced cancer stem cell properties in HepG2 through PI3K/Akt signaling. 30500989

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Human metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is an abundant nuclear-localized long noncoding RNA (lncRNA) that has significant roles in cancer. 31717552

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Recent studies suggest onco-regulatory roles for two long non-coding RNAs (lncRNAs), MALAT1 and HOTAIR, in various malignancies; however, these lncRNAs have not been previously examined in neuroendocrine neoplasms (NENs) of gastroenteropancreatic origins (GEP-NENs). 30600442

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE This review presents the current level of knowledge on the most studied cancer-related lncRNAs, such as the metastasis associated lung adenocarcinoma transcript 1 (MALAT1), the Hox transcript antisense intergenic RNA (HOTAIR), or the X-inactive specific transcript (XIST), as well as more recently discovered forms, and their potential roles in different types of cancer. 30654440

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Notably, different or opposite phenotypes resulting from different strategies for inactivating <i>MALAT1</i> have been observed, which led to distinct models for <i>MALAT1'</i>s functions and mechanisms of action in cancer and metastasis. 30781877

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE The present results identified a significant association between MALAT1 abundance and poor OS in patients with digestive system malignancies, with a pooled hazard ratio (HR) of 1.62 [95% confidence interval (CI), 1.35-1.88; P<0.001]. 30719108

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 GeneticVariation BEFREE Neither was the association between the MALAT-1 SNPs and progression factors of HCC, including TNM staging, metastasis, and cancer embolus; Overall, this study suggested that tagSNPs rs11227209, rs619586, and rs3200401 at MALAT-1 were not significantly associated with HCC susceptibility. 31350456

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 GeneticVariation BEFREE By characterizing this sense/anti-sense pair we uncovered the complexity of MALAT1 locus regulation, describing new potential candidates for cancer targeting. 31382922

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Tongue squamous cell carcinoma (TSCC) is the second most common malignancy in oral carcinoma. lncRNA metastasis-associated lung adenocarcinoma transcript 1 (<i>MALAT1</i>) was regarded as an oncogenic factor in various carcinomas. 30863103

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE long noncoding RNA Metastasis-associated lung adenocarcinoma transcript 1 might be a usable biomarker for cancer diagnosis and detection. 30561226

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Metastasis associated lung adenocarcinoma transcript 1 (MALAT1) is a highly conserved long noncoding RNA, which has been related to various pathological processes, including cancer. 31733641

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Antisense Oligonucleotide-Conjugated Nanostructure-Targeting lncRNA MALAT1 Inhibits Cancer Metastasis. 30548064

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA, is associated with several cancer types, however, how it interacts with CCL21 to regulate MF progression, remains unclear. 31028199

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Collectively, our study demonstrates that cancer cell-specific chromatin-chromatin interactions are formed at the <i>MALAT1</i> locus under hypoxia, implicating a novel mechanism of MALAT1 regulation in cancer. 31167784

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE MALAT1 plays a significant role in many malignancies, including HCC. 31347327

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Here, we investigated the role of MALAT1 in regulating cancer glucose metabolism. 30914432

2019

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Most well documented in cancer, one prominent intergenic lncRNA known as MALAT1 is notorious for its role in impacting epigenetic mechanisms. 29695738

2018

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE Correlation study between long non-coding RNA MALAT1 and radiotherapy efficiency on cervical carcinoma and generation of radiotherapy resistant model of cancer. 30178834

2018

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE As a type of new targets for prognosis of malignancies, long non-coding RNA MALAT1 (metastasis-associated lung adenocarcinoma transcription 1) is associated with proliferation and metastatic abilities of several malignancies. 29416769

2018

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 Biomarker BEFREE LncRNA MALAT1 Promotes Cancer Metastasis in Osteosarcoma via Activation of the PI3K-Akt Signaling Pathway. 30481748

2018

Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.100 AlteredExpression BEFREE The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long noncoding RNA and its overexpression is associated with the development of many types of malignancy. 29577871

2018