Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 Biomarker BEFREE In this study, we evaluated the exact role and the regulation mechanism of miR-22 and miR-214 in colon cancer. 30698996

2019
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 Biomarker BEFREE In mice, miR-22 and its inducers inhibited the growth of xenograft colon cancer. 30252536

2019
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 Biomarker BEFREE Concordant microRNA/mRNA expressions were identified in association with DBP exposure for hsa-mir-22-3p and hsa-miR-146a-5p and their targets RCOR1 and TLR4, both related to colon cancer in association with DBP exposure. 29122314

2018
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 AlteredExpression BEFREE In humans, the expression levels of miR-22 and CCNA2 are inversely correlated in liver and colon cancers. 25596928

2015
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 Biomarker BEFREE Collectively, these data suggest that miR-22 may act as a tumor suppressor in colon cancer, most likely by targeting TIAM1 expression. 23440286

2013
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 Biomarker BEFREE To explore whether miR-22 is an important player in the development of chemoresistance in colon cancer, we overexpressed miR-22 and subsequently tested its role in cell proliferation, apoptosis, survival, and associated signaling in p53-mutated HT-29 and HCT-15 cells, and p53 wild-type HCT-116 cells. 21594648

2011
Entrez Id: 407004
Gene Symbol: MIR22
MIR22
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.070 Biomarker BEFREE Taken together, our data suggest that miR-22 might have an anti-angiogenic effect in colon cancer. 21629773

2011