Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5423
Gene Symbol: POLB
POLB
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.330 Biomarker CTD_human Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells. 25030372

2014
Entrez Id: 5423
Gene Symbol: POLB
POLB
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.330 GeneticVariation BEFREE Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation. 22573322

2012
Entrez Id: 5423
Gene Symbol: POLB
POLB
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.330 GeneticVariation BEFREE One of the DNA polymerase beta colon cancer-associated mutants, K289M, has been shown to synthesize DNA with a lower fidelity than wild-type Pol beta. 15280658

2004
Entrez Id: 5423
Gene Symbol: POLB
POLB
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.330 GeneticVariation BEFREE We have found a significant concordance between the in vitro replication errors of human DNA polymerase beta and in vivo point mutations of the adenomatous polyposis coli (APC) gene that leads to colon cancer. 12036944

2002