DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Malignant neoplasm of endometrium ×

Gene: PIK3R2 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5296
Gene Symbol:	PIK3R2

PIK3R2

CUI:	C0007103
Disease:	Malignant neoplasm of endometrium

Malignant neoplasm of endometrium

0.320

Biomarker

BEFREE

New routes to old places: PIK3R1 and PIK3R2 join PIK3CA and PTEN as endometrial cancer genes.

22586352

2011

Entrez Id:	5296
Gene Symbol:	PIK3R2

PIK3R2

CUI:	C0007103
Disease:	Malignant neoplasm of endometrium

Malignant neoplasm of endometrium

0.320

GeneticVariation

BEFREE

High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.

21984976

2011

Entrez Id:	5296
Gene Symbol:	PIK3R2

PIK3R2

CUI:	C0007103
Disease:	Malignant neoplasm of endometrium

Malignant neoplasm of endometrium

0.320

CausalMutation

CGI