Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.050 Biomarker BEFREE The increased levels of urokinase-type plasminogen activator (uPA), uPA-receptor (uPAR) and type-1 PA inhibitor (PAI-1) are reported in human renal cell carcinoma (RCC). 16289236

2006

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.050 AlteredExpression BEFREE We conclude that uPA- and uPAR are overexpressed in RCC and could function as tumour markers. 16077991

2005

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.050 AlteredExpression LHGDN We conclude that uPA- and uPAR are overexpressed in RCC and could function as tumour markers. 16077991

2005

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.050 Biomarker BEFREE We determined the role of the VHL tumor suppressor gene in the regulation of the uPA system in RCC. 10485495

1999

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.050 Biomarker BEFREE The modest increase in uPA receptor expression may lead to a normalization of uPA antigen content in RCC; however, it is not sufficient to substantially increase tumor tissue-uPA content over the level of normal non-tumorous kidney tissue. 7604879

1995

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.050 Biomarker BEFREE A cell line derived from a human kidney carcinoma produces in vitro the urinary type of plasminogen activator (urokinase). 6386832

1984