Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.340 Biomarker BEFREE Therefore, targeting GRK2 by different strategies emerges as a potentially relevant approach to treat cardiovascular disease, obesity, type 2 diabetes, or NAFLD, pathological conditions which are frequently interconnected and present as co-morbidities. 30837878

2019
Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.340 GeneticVariation BEFREE Areas covered: Based on this premise, GRK2 inhibition or its genetic deletion has been tested in several disparate animal models of cardiovascular disease, showing to protect the heart from adverse remodeling and dysfunction. 29166798

2018
Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.340 AlteredExpression BEFREE The G-protein-coupled receptor kinase 2 (GRK2) plays a major role in cardiovascular diseases, and its expression is increased in heart failure. 29905975

2018
Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.340 Biomarker BEFREE GRK2 as negative modulator of NO bioavailability: Implications for cardiovascular disease. 28077324

2018
Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases 		0.340 Biomarker CTD_human The two most widely expressed GRKs (GRK2 and GRK5) play a role in cardiovascular disease and thus represent important targets for the development of novel therapeutic drugs. 26032411

2015