Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 GeneticVariation BEFREE Haploview analysis showed that the ACC (rs151290, rs2237892 and rs2237895) haplotype is the most significant risk allele combination for CVD, while CCA is the most significant risk haplotype for co-morbidity with T2D. 28863213

2019

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 Biomarker BEFREE Relationship of the Blood Pressure Categories, as Defined by the ACC/AHA 2017 Blood Pressure Guidelines, and the Risk of  Development of Cardiovascular Disease in Low-Risk Young  Adults: Insights From a Retrospective Cohort of Young Adults. 31140347

2019

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 Biomarker BEFREE Ten-year CVD risk was estimated with American College of Cardiology/American Heart Association Atherosclerotic Cardiovascular Disease (ACC/AHA ASCVD) Risk Estimator (2013), Framingham Risk Score (Framingham Risk Score [FRS] 2008), and the World Health Organisation/International Society of Hypertension (WHO/ISH) risk prediction chart for Africa Region D. Kappa statistic was used to determine agreement among the estimators. 29050979

2018

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 Biomarker BEFREE In an HIV clinical care cohort, the ACC/AHA cholesterol guidelines recommend a higher proportion of patients for statin therapy and identify an increased proportion of patients with a CVD event compared with ATPIII. 30619912

2018

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 Biomarker BEFREE Eligible patients of enrolled primary care providers are aged 40-75 and have elevated risk of cardiovascular disease by American College of Cardiology/American Heart Association (ACC/AHA) guidelines. 30367991

2018

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 GeneticVariation BEFREE Initiating cholesterol-lowering medications for primary prevention, as specified in the ACC/AHA 2013 guidelines, for patients with high LDL-C and diabetes is associated with reduced CVD event risks and lower health care costs. 30362921

2018

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 Biomarker BEFREE We used the Cardiovascular Disease Policy Model to estimate the cost-effectiveness of the ACC/AHA guideline relative to current use, Adult Treatment Panel III guidelines, and universal statin use in all men 45 to 74 years of age and women 55 to 74 years of age over a 10-year horizon from 2016 to 2025. 28687710

2017

Entrez Id: 31
Gene Symbol: ACACA
ACACA
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.080 Biomarker BEFREE However, the reclassification improvement was not substantially different between model 6 and the ACC/AHA CVD Pooled Cohort risk equations or between model 6 and the FHS. 27437649

2016