Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.340 Biomarker BEFREE Tlr2 Deficiency is Associated with Enhanced Elements of Neuronal Repair and Caspase 3 Activation Following Brain Ischemia. 30808918

2019

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.340 Biomarker BEFREE This indicates no involvement of the BNIP3 gene along with the CASP3 gene in the CA3 region of the hippocampus in delayed neuronal death after brain ischemia. 31707369

2019

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.340 Biomarker BEFREE Nesfatin-1 significantly reduced caspase-3 (P < 0.01) and microglial activation (P < 0.01) and improved spatial memory impairments (P < 0.05) induced by brain ischemia. 29956089

2018

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.340 Biomarker CTD_human Tamoxifen neuroprotection in cerebral ischemia involves attenuation of kinase activation and superoxide production and potentiation of mitochondrial superoxide dismutase. 17901229

2008

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.340 AlteredExpression LHGDN Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia. 12605885

2003

Entrez Id: 836
Gene Symbol: CASP3
CASP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.340 Biomarker CTD_human Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. 11756504

2002