Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.030 Biomarker BEFREE These data implicate replication in skeletal muscle cells and release of IL-6 as important mediators of CHIKV disease. 31794434

2020

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.030 Biomarker BEFREE Analysis of inflammatory cytokines revealed a strong increase of interferon (IFN)-α and IFN-β, as well as interleukin-6, suggesting a possible role of type-I IFN in the cytokine storm, which may be correlated with unfavorable prognosis of CHIKV infection. 30539034

2018

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.030 Biomarker BEFREE Interestingly, severe CHIKF patients had significantly lower concentrations of circulating IL-8 than the other groups of patients, suggesting that high concentrations of IL-6 and MCP-1 with low concentrations of IL-8 may be a determinant of severe chikungunya virus infection. 22188545

2012