Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 400668
Gene Symbol: PRSS57
PRSS57
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.050 Biomarker BEFREE An amino acid change in nsP4 of chikungunya virus confers fitness advantage in human cell lines rather than in <i>Aedes albopictus</i>. 31613205

2019

Entrez Id: 400668
Gene Symbol: PRSS57
PRSS57
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.050 Biomarker BEFREE Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus. 28236746

2017

Entrez Id: 400668
Gene Symbol: PRSS57
PRSS57
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.050 Biomarker BEFREE Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activities. 28390873

2017

Entrez Id: 400668
Gene Symbol: PRSS57
PRSS57
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.050 Biomarker BEFREE Sequencing the nsp4 gene of the discordant positive sample indicated the presence of chikungunya RNA, and mismatches to the primer binding sites of the CDC assay. 28633900

2017

Entrez Id: 400668
Gene Symbol: PRSS57
PRSS57
CUI: C0008055
Disease: Chikungunya Fever
Chikungunya Fever
0.050 Biomarker BEFREE In this study we have developed and validated a triplex real time reverse transcription PCR assay using hydrolysis probes targeting the non-structural 5 (NS5) region of ZIKV, non-structural protein 4 (nsP4) from CHIKV and 3' untranslated region (3'UTR) of DENV 1-4. 27614319

2016