Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0008925
Disease: Cleft Palate
Cleft Palate 		0.030 AlteredExpression BEFREE We found that cleft palate pathogenesis in Pax9-deficient embryos is accompanied by significantly reduced expression of Axin2, an endogenous target of canonical Wnt signaling, in the developing palatal mesenchyme, particularly in the posterior regions of the palatal shelves. 28692808

2017
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0008925
Disease: Cleft Palate
Cleft Palate 		0.030 Biomarker BEFREE Comparison between cleft and control groups showed a trend for association for AXIN2 with incomplete cleft palate (p = .006) and CDH1 with unilateral CL/P (p = .03 for left CL/P and p = .04 for right CL/P). 18683894

2009
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0008925
Disease: Cleft Palate
Cleft Palate 		0.030 GeneticVariation BEFREE Some genes affecting early tooth development (MSX1, AXIN2) are associated with tooth agenesis and systemic features (cleft palate, colorectal cancer). 18499550

2008