Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0009319
Disease: Colitis
Colitis
0.530 Biomarker BEFREE These activated inflammatory mediators and pathology of colitis were completely suppressed by treatment with a NO scavenger, 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide, as well as an iNOS inhibitor, aminoguanidine. 24992835

2014

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0009319
Disease: Colitis
Colitis
0.530 AlteredExpression BEFREE Analysis of human biopsies of colitis and colon cancer using immunohistochemistry revealed elevated iNOS protein expression levels, which were strongly paralleled by increased expression of nitrotyrosine suggesting that iNOS has been highly activated in these tissues. 22417974

2012

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0009319
Disease: Colitis
Colitis
0.530 Biomarker BEFREE NO increases WISP-1 expression both in vitro and in vivo, suggesting a new role for iNOS and NO in colitis. 19238344

2009

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0009319
Disease: Colitis
Colitis
0.530 Biomarker CTD_human Resistance to DSS-induced colitis was lost when wild-type (wt) BM was used to reconstitute iNOS-/- mice. 17449036

2007

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0009319
Disease: Colitis
Colitis
0.530 Biomarker RGD Expression of iNOS mRNA associated with suppression of colonic contraction in rat colitis. 16866779

2006

Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0009319
Disease: Colitis
Colitis
0.530 Biomarker CTD_human Colitis and interleukin 1beta up-regulate inducible nitric oxide synthase and superoxide dismutase in rat myenteric neurons. 8698225

1996