Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.420 AlteredExpression BEFREE While exposing the polygenic architecture of circulating lipids and the underpinnings of dyslipidaemia, these genome-wide association studies (GWAS) have provided further evidence of the critical role that lipids play in coronary heart disease (CHD) risk, as indicated by the 2.7-fold enrichment for macrophage gene expression in atherosclerotic plaques and the association of 25 loci (such as PCSK9, APOB, ABCG5-G8, KCNK5, LPL, HMGCR, NPC1L1, CETP, TRIB1, ABO, PMAIP1-MC4R, and LDLR) with CHD. 29800275

2018
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.420 Biomarker BEFREE The impact of candidate ABCG5/8 SNPs on CHD was evaluated in a dominant genetic model with stepwise multiple regression analysis. 24691589

2014
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.420 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282

2011
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.420 Biomarker CTD_human Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. 19060911

2009