Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.040 GeneticVariation BEFREE To carry out a systematic review and meta-analysis of previous studies examining the association between acetaminophen and NSAIDs including cyclooxygenase (COX-2) inhibitors use, and risk of Crohn's disease (CD) and ulcerative colitis (UC) exacerbation. 29620794

2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.040 GeneticVariation BEFREE The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease. 21124790

2010
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.040 GeneticVariation BEFREE An effect of the COX-2 polymorphism on both CD and UC was shown which is compatible with the presence of a recessive allele in linkage equilibrium with the SNP marker in the COX-2 gene. 18819034

2009
Entrez Id: 4513
Gene Symbol: COX2
COX2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.040 Biomarker BEFREE COX-2 protein was not detected in normal epithelial cells but was detected in Crohn's disease and ulcerative colitis epithelial cells. 9679035

1998