Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 GeneticVariation BEFREE We explored the association between mutations in the hemochromatosis (HFE) gene and disease severity in adults with CF. 30291871

2019
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 GeneticVariation BEFREE HFE gene mutations modify disease severity in CF, through probable effects on iron homeostasis. 20199637

2010
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 GeneticVariation BEFREE The possible implication of the hemochromatosis gene as a CF modifier locus was analyzed because the 2 children had the same genotype. 18078365

2008
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 Biomarker BEFREE We determined the genotype of four proposed genetic risk factors for hepatocellular carcinoma [hereditary hemochromatosis (HFE 63 and 282), alpha(1)-antitrypsin deficiency (AAT 342) and cystic fibrosis (CFTR 508)] on formalin-fixed tissue samples, stored for up to 25 years, from 318 patients diagnosed with hepatocellular carcinoma and on plasma or serum samples from 31 of these patients. 15668502

2005
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 GeneticVariation LHGDN HFE status of CF allele carriers and CF patients (Delta F508) homozygotes with and without meconium ileus was determined. 12885340

2003
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 Biomarker BEFREE HFE status of CF allele carriers and CF patients (Delta F508) homozygotes with and without meconium ileus was determined. 12885340

2003
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 Biomarker BEFREE These data are suggestive of a relationship between the development of meconium ileus or other gastrointestinal diseases in CF and the HFE gene. 10464603

1998
Entrez Id: 3077
Gene Symbol: HFE
HFE
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.160 SusceptibilityMutation CLINVAR