Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 AlteredExpression BEFREE We found that long-term DCA administration improved cognitive function in VD rats, reduced brain infarct size and brain atrophy, increased VEGF and bFGF levels <i>in vivo</i>, promoted angiogenesis in damaged areas, and significantly improved EPC function in VD rats. 31156438

2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 AlteredExpression BEFREE Rats in the VaD model group demonstrated relative hypomethylation in the promoter region and increased mRNA expression of the hippocampal genes vascular endothelial growth factor (VEGFA) and kinase insert domain receptor, but only differences in VEGFA mRNA expression levels were determined to be statistically significant. 29749552

2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 AlteredExpression BEFREE Our study suggests that VEGF levels in the CSF do not reflect the cerebral vascular alterations in either AD or VaD patients. 29933741

2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 Biomarker BEFREE In addition, the VaD + EE group showed significantly increased expression of BDNF, pCREB, and VEGF in the hippocampus compared to the VaD group. 28032515

2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 AlteredExpression BEFREE Genes that were upregulated in VaD were MMP9 and VEGFA. 25024308

2014
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 GeneticVariation LHGDN Haplotype analysis of single nucleotide polymorphisms in VEGF gene for vascular dementia. 16583410

2006
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		0.060 GeneticVariation BEFREE Haplotype analysis of single nucleotide polymorphisms in VEGF gene for vascular dementia. 16583410

2006