Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE High plasma levels of IL-6, CRP and SAA were associated with unstable CAD, as well as established risk factors including type 2 diabetes mellitus, smoking, low glomerular filtration rate, low TGs and low HDL-C. After adjusting for established cardiovascular risk markers and the other two inflammatory markers, SAA was found to be an independent risk factor for cardiovascular mortality after a short-term follow-up (6 months-1 year) with a HR per SD of 1.41. 31263995

2020

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation BEFREE CRP gene variants may contribute to the risk of early-onset T2DM by affecting the serum CRP level. 31471424

2020

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE This technique has been used to provide evidence of causal associations of serum estradiol concentrations, smoking, body mass index, and type 2 diabetes with bone mineral density and the lack of associations of serum thyroid stimulating hormone, urate, C-reactive protein, and 25‑hydroxyvitamin D concentrations with bone mineral density in generally healthy populations. 30321669

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE This study aimed to evaluate the effect of DPP-4i on modulating serum levels of C-reactive protein (CRP) in T2DM. 31208420

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE The main objective of the current study was to understand how CRP was related to trauma, dissociation, PTSD and MDD in a sample of 55 traumatized African American women with type 2 diabetes mellitus recruited from an urban hospital. 31306866

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE Associations have been suggested of high-dose ionising radiation exposure with type-2 diabetes and elevated levels of C-reactive protein, a marker of chronic inflammation. 30894578

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Association of extracellular heat shock protein 70 and insulin resistance in type 2 diabetes; independent of obesity and C-reactive protein. 30255491

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE The application of PCT to predict local infection in patients with T2DM was identified to be inferior to CRP, but its ability to predict sepsis was concluded to be the best when compared with CRP, white blood cell count and neutrophil percent. 31258707

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes. 30455330

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE In conclusion, besides consideration of CRP levels alone, our findings suggested that IL-6 outstandingly plays a contributing role in T2DM progression and elevated TNF-<i>α</i> levels over time could be a potential predictor of T2DM. 31485456

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE As many factors linked to obesity can modulate CRP in T2DM, we comprehensively revisited the cardiometabolic phenotype of patients with normal or raised CRP, taking into account the sexual dimorphism of its serum value. 31477553

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE In patients with CAD and newly diagnosed T2DM on stable statin therapy, liraglutide combined with metformin may improve the atherogenic LDL lipid profile and CRP. 31326727

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE Association of retinol binding protein-4, cystatin C, homocysteine and high-sensitivity C-reactive protein levels in patients with newly diagnosed type 2 diabetes mellitus. 31572465

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Effects of Coenzyme Q10 Supplementation on Serum Values of Gamma-glutamyl transferase, Pseudocholinesterase, Bilirubin, Ferritin, and High-Sensitivity C-Reactive Protein in Women with Type 2 Diabetes. 29365333

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE Association between specific plasma ceramides and high-sensitivity C-reactive protein levels in postmenopausal women with type 2 diabetes. 31185304

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Furthermore, overweight/obese individuals showed positive correlation of both plasma C-Reactive Protein and triglyceride/HDLc-index with LGI-Ob; and high LGI-Ob score was associated with greater hypertension (<i>p</i> = 0.047), Type 2 diabetes (<i>p</i> = 0.026), and metabolic risk (<i>p</i> = 0.021). 30704070

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE CRP and continuous use of ADM predicted incident T2DM in the PLB group. 29016549

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE In conclusion, we found positive associations between CRP and incident T2DM in a large population-based Korean cohort. 30872696

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Training reduced plasma levels of TNF-<i>α</i> (1.9-fold in controls and 2.2-fold in patients with T2DM) and CRP (1.4-fold in controls and 3.4-fold in patients with T2DM). 31827375

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Last, we identified early personal molecular signatures in one individual that preceded the onset of T2D, including the inflammation markers interleukin-1 receptor agonist (IL-1RA) and high-sensitivity C-reactive protein (CRP) paired with xenobiotic-induced immune signalling. 31142858

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE Clinical [blood pressure; cataract status; MPOD] and anthropometric [waist (cm); weight (kg); hip (cm)] measurements were taken, and a blood sample drawn for analysis of serum biomarkers [lipoproteins; inflammatory markers (C reactive protein and vitamin-D)].<b>Results</b>: One-way ANOVA revealed lower MPOD in subjects with Type 2 diabetes relative to controls (<i>p</i> = .047). 31225969

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE In addition, CC genotyped T2D patients had higher levels of CRP compared to CT and TT genotyped T2D patients, (p < 0.01). 30521849

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression BEFREE Does synbiotic supplementation affect body weight, body mass index, and high-sensitivity C-reactive protein levels in patients with type 2 diabetes? Protocol for a systematic review and meta-analysis. 31804340

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE A systematic search was performed in the ISI Web of science, PubMed and Scopus to find articles related to the effect of the green tea on CRP, malondealdehyde (MDA) and total antioxidant capacity (TAC) in T2DM patients, up to June 2019. 31519281

2019

Entrez Id: 1401
Gene Symbol: CRP
CRP
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker BEFREE We investigated associations of sCD14, interleukin-6 (IL-6), CRP, and white blood cell (WBC) count with insulin resistance (quantitative insulin-sensitivity check index and HOMA 2 of insulin resistance) and incident type 2 diabetes in a population-based cohort of older adults. 31471378

2019