Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker BEFREE Only NfL concentration in the group with DS showed a significant positive association with age. 30902060

2019
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker BEFREE Plasma NF-L is associated with progressive neurodegeneration as well as with declines in cognitive and functional measures in adults with DS. 31156181

2019
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker BEFREE NF-L is a biomarker for neurodegeneration in DS with potential for use in future clinical trials to prevent or delay dementia. 29631614

2018
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		0.040 Biomarker BEFREE Antibodies to dephospho-NF-M, NF-M, and NF-L were more common in DS samples than in controls. 19758141

2009