DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Down Syndrome ×

Gene: VPREB1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	7441
Gene Symbol:	VPREB1

VPREB1

CUI:	C0013080
Disease:	Down Syndrome

Down Syndrome

0.010

GeneticVariation

BEFREE

In total, 50% of DS ALL patients had ≥1 deletion in the B-cell development genes: PAX5 (12%), VPREB1 (18%) and IKZF1 (35%).

2012