Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.050 Biomarker BEFREE Correction: The role of substance P in epilepsy and seizure disorders. 31191827

2019
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.050 Biomarker BEFREE Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats. 30963545

2019
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.050 Biomarker BEFREE Significant findings included reduction in somatostatin neurons and neurokinin 1 receptor labelling in the ventrolateral medulla in sudden death in epilepsy compared to controls (P < 0.05). 29608654

2018
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.050 Biomarker BEFREE Newest studies show that several mechanisms may explain the excitatory effects of the SP/NK-1 receptor signaling pathway in epilepsy. 28474564

2018
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0014544
Disease: Epilepsy
Epilepsy 		0.050 Biomarker BEFREE In this review, we summarize the present literature to expound the role of SP in epilepsy, and provide hypotheses for potential mechanisms. 29100462

2017