Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 AlteredExpression BEFREE TNF-α stimulation further upregulated the expression of NF-κB1, STAT-6 in tandem with Ras-MEK signaling system in U87MG cells, which emphasized the possible involvement of these signaling hubs in the glioma microenvironment. 30839135

2019
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 GeneticVariation BEFREE NFKB1 -94ins/delATTG and TLR4Asp299Gly polymorphisms are associated with increased glioma cancer risk in a Turkish population. 30450997

2019
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 GeneticVariation BEFREE A del/ins polymorphism of the NF-κB1 gene (OR 4.27, 95% CI 2.43-7.50, p<0.001) was also found to be associated with glioma. 28777431

2018
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 Biomarker BEFREE Thus, high-grade glioma T cells play a key role in directing M2 polarization of tumor myeloid cells, and reducing NF-κB p50 in both tumor myeloid cells and T cells may contribute to glioma therapy. 30030559

2018
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 AlteredExpression BEFREE Results showed that the expression of NF-κB1 in human glioma tissues and glioma cell lines, SHG44 and U87, was significantly higher compared to noncancerous brain tissues and that the expression increased with increasing degrees of tumor malignancy. 28919779

2017
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 AlteredExpression BEFREE p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50. 22810421

2012
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 AlteredExpression LHGDN Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1. 18316612

2008
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 Biomarker LHGDN Pregabalin and gabapentin inhibit substance P-induced NF-kappaB activation in neuroblastoma and glioma cells. 18615578

2008
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0017638
Disease: Glioma
Glioma 		0.090 AlteredExpression BEFREE Aneuploid nuclei of glial tumors showed enhanced expression of p105 relative to diploid cells of the same specimen. 2377285

1990