Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017638
Disease: Glioma
Glioma 		0.060 Biomarker BEFREE In summary, Lrig1 is a haploinsufficient suppressor of PDGFB-driven glioma, possibly in part via negative regulation of MET-driven cell migration and invasion. 29391393

2018
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017638
Disease: Glioma
Glioma 		0.060 Biomarker BEFREE The phenotype of Lrig2E12-/- mice showed that Lrig2 was a promoter of PDGFB-induced glioma, and Lrig2 appeared to have important molecular and developmental functions that were distinct from those of Lrig1 and Lrig3. 24023893

2013
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017638
Disease: Glioma
Glioma 		0.060 AlteredExpression BEFREE Expression of PDGFB is thought to be important in the pathogenesis of glioma and several animal models of cerebral glioma based on PDGF expression have been described. 18922925

2008
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017638
Disease: Glioma
Glioma 		0.060 Biomarker LHGDN High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. 17292826

2007
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017638
Disease: Glioma
Glioma 		0.060 Biomarker LHGDN Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells. 14997209

2004
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017638
Disease: Glioma
Glioma 		0.060 AlteredExpression BEFREE Activation of glioma c-sis gene expression is therefore not the result of a gross rearrangement or amplification of the c-sis gene. 2585029

1989