Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5228
Gene Symbol: PGF
PGF
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 AlteredExpression BEFREE This review discusses PlGF and its signalling pathways and highlights the potential of blocking the bioactivity of this growth factor to treat irreversible visual loss due to the two main forms of AMD. 31055948

2019
Entrez Id: 5228
Gene Symbol: PGF
PGF
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 AlteredExpression BEFREE This study identified a rare, functional promoter variant in the PGF gene that increases PGF transcription activity and confers a 5-fold risk to neovascular AMD. 31377148

2019
Entrez Id: 5228
Gene Symbol: PGF
PGF
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 AlteredExpression BEFREE At baseline, the aqueous humor levels of sVEGFR-1, sVEGFR-2, VEGF, and PlGF were significantly higher in the AMD group than in the control group. 30534004

2018
Entrez Id: 5228
Gene Symbol: PGF
PGF
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 Biomarker BEFREE The study results suggest that PGF may play a role in scar formation in neovascular age-related macular degeneration (AMD) and that the inhibition of PGF may be a promising target for the prevention and treatment of AMD. 29769799

2018