Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 GeneticVariation BEFREE COX-2 -765 C allele genotype, drinking history and family history of liver cancer may increase the susceptibility to hepatitis B-related liver cancer in Gansu province, China. 21800055

2012
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 AlteredExpression BEFREE Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter. 21401943

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 AlteredExpression BEFREE In addition, we also demonstrated that COX-2 expression activated by IL-8 was mediated through CREB and C/EBP, which maintains the inflammatory environment associated with HBV infection. 21957142

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 GeneticVariation BEFREE COX-2 -899C carriers may have an increased risk for hepatitis B-related liver cancer. 22340386

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker BEFREE Potent cell growth inhibitory effects in hepatitis B virus X protein positive hepatocellular carcinoma cells by the selective cyclooxygenase-2 inhibitor celecoxib. 18506760

2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker LHGDN COX-2 mediates hepatitis B virus X protein abrogation of p53-induced apoptosis. 18601905

2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 Biomarker BEFREE In this study, we investigated the relationship between the transactivator HBx and COX-2 in hepatitis B virus-associated chronic liver diseases. 15218507

2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.080 AlteredExpression LHGDN The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. 12488433

2002