Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.400 CausalMutation CLINVAR Arthrogryposis as neonatal presentation of Loeys-Dietz syndrome due to a novel TGFBR2 mutation. 28344185

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.400 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.400 Biomarker HPO

Entrez Id: 6899
Gene Symbol: TBX1
TBX1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 GeneticVariation BEFREE Increased incidences of inguinal hernia have been reported in patients with 22q11.2 microdeletion syndrome, which is mainly caused by TBX1 gene mutations. 24295890

2014
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 GeneticVariation BEFREE We aimed to evaluate whether the functional Sp1 binding site polymorphism within intron 1 of the collagen type I, alpha 1 (COL1A1) gene was associated specifically with inguinal hernia disease. 23925543

2014
Entrez Id: 2006
Gene Symbol: ELN
ELN
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker BEFREE Disorders of the microfibril, elastin, collagen, and the glycosaminoglycan component of the extracellular matrix can result in an increase in the likelihood of inguinal hernia. 19573673

2009
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 GeneticVariation BEFREE In these families, the presence of apparently causative TCF8 mutations is associated with abdominal and inguinal hernias. 17935237

2007
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker BEFREE The alpha 1(I)/alpha 1(III) collagen ratios were shown to be 6.3 +/- 0.34 in fibroblasts from control individuals and 3.0 +/- 0.25 in fibroblasts from patients with inguinal hernias. 7710461

1993
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker HPO

Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker HPO

Entrez Id: 6899
Gene Symbol: TBX1
TBX1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker HPO

Entrez Id: 2006
Gene Symbol: ELN
ELN
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker HPO

Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.110 Biomarker HPO

Entrez Id: 51352
Gene Symbol: WT1-AS
WT1-AS
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 GeneticVariation GWASCAT A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. 26686553

2015
Entrez Id: 64641
Gene Symbol: EBF2
EBF2
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 GeneticVariation GWASCAT A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. 26686553

2015
Entrez Id: 64220
Gene Symbol: STRA6
STRA6
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 871
Gene Symbol: SERPINH1
SERPINH1
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 134701
Gene Symbol: RIPPLY2
RIPPLY2
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 8295
Gene Symbol: TRRAP
TRRAP
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 25942
Gene Symbol: SIN3A
SIN3A
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 23322
Gene Symbol: RPGRIP1L
RPGRIP1L
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 2812
Gene Symbol: GP1BB
GP1BB
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO

Entrez Id: 56623
Gene Symbol: INPP5E
INPP5E
CUI: C0019294
Disease: Hernia, Inguinal
Hernia, Inguinal 		0.100 Biomarker HPO