Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 Biomarker BEFREE Cellular Senescence Markers p16INK4a and p21CIP1/WAF Are Predictors of Hodgkin Lymphoma Outcome. 26199387

2015
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 Biomarker BEFREE We showed effective targeting of the CDKN1A 3' UTR by miR-17/106b in HL cell lines in a luciferase reporter assay and up-regulation of p21 protein levels upon anti-miR-17 treatment of KM-H2 cells. 21953646

2011
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 Biomarker BEFREE Clinically, suppression of p21cip1/waf1 in EBV+ HLs was associated with a worse 2-year disease-free survival rate (45% for EBV+ HLs vs. 77% for EBV- HLs, p = 0.002). 20144199

2010
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 AlteredExpression BEFREE Retinoblastoma gene product and P21 (WAF1, CIP1) protein expression in non Hodgkin's lymphomas: a multivariate survival analysis. 11426536

2001
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 GeneticVariation BEFREE The pattern of the p53-transactivated genes mdm2 and p21/WAF1 suggests that inactivating mutations of p53 are rare in HD. 9349231

1997
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 Biomarker BEFREE The pattern of p53 and p21WAF1/CIP1 immunoreactivity in non-Hodgkin's lymphomas predicts p53 gene status. 9360843

1997
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 AlteredExpression BEFREE MDM2 and p21WAF1/CIP1, wild-type p53-induced proteins, are regularly expressed by Sternberg-Reed cells in Hodgkin's disease. 8943816

1996
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.080 AlteredExpression BEFREE p21/WAF1 cyclin-kinase inhibitor expression in non-Hodgkin's lymphomas: a potential marker of p53 tumor-suppressor gene function. 8916968

1996