Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 Biomarker BEFREE We sought to determine the utility of the novel YE361 STAT6 rabbit monoclonal antibody in Hodgkin lymphoma and diagnostically challenging B- and T-cell non-Hodgkin lymphoma entities with Hodgkin-like features. 31822802

2019
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 AlteredExpression BEFREE In the present study the JAK1/2 inhibitor ruxolitinib reduced phosphorylation of STAT3 and STAT6 and expression of c-Myc in the HL cell line HDLM-2. 26811457

2016
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 GeneticVariation BEFREE A reduced risk for HL was observed for the heterozygous genotype of the STAT6 SNP (rs324011). 21418178

2011
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 AlteredExpression BEFREE Because Hodgkin/Reed-Sternberg cells are known to secrete IL-13, to have constitutively activated STAT6, and to be closely surrounded by CD4(+) T cells, these mechanisms may be involved in the expression of LMP-1 in EBV-positive chronic HLs. 20876453

2011
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 AlteredExpression BEFREE Somatic hypermutation of SOCS1 in lymphocyte-predominant Hodgkin lymphoma is accompanied by high JAK2 expression and activation of STAT6. 17652621

2007
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 AlteredExpression LHGDN In lymphocyte-predominant Hodgkin lymphoma SOCS1 function may thus be frequently impaired by mutations, and this may contribute to high JAK2 expression and activation of the JAK2/STAT6 pathway. 17652621

2007
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 AlteredExpression LHGDN A detailed inventory of DNA copy number alterations in four commonly used Hodgkin's lymphoma cell lines. 17606441

2007
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease 		0.070 Biomarker BEFREE STAT6 was constitutively phosphorylated in 5 of 5 HL cell lines and in HRS cells from 25 of 32 (78%) classical HL cases. 11781246

2002