Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.040 GeneticVariation BEFREE Blackcurrant Extract Ameliorates Hyperglycemia in Type 2 Diabetic Mice in Association with Increased Basal Secretion of Glucagon-Like Peptide-1 and Activation of AMP-Activated Protein Kinase. 30175788

2018
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.040 Biomarker BEFREE We found that hyperglycemia impaired autophagy in HUVECs through the inhibition of AMP-activated protein kinase (AMPK), which directly led to endothelial cell damage. 26644014

2016
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.040 AlteredExpression BEFREE The activation of AMP-activated protein kinase (AMPK) has a beneficial effect on hyperglycaemia. 26198388

2016
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.040 Biomarker BEFREE 5'-AMP elevated blood glucose in mice deficient in adenosine receptors with equal efficiency as wild-type mice. 22068600

2012