Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.120 Biomarker BEFREE Among the many genes that increase the risk of autoimmune conditions, the risk allele encoding the W620 variant of protein tyrosine phosphatase N22 (PTPN22) is shared between multiple rheumatic diseases, suggesting that it plays a fundamental role in the development of immune dysfunction. 30507064

2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.120 GeneticVariation GWASCAT Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08. 23055271

2012
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.120 GeneticVariation GWASDB Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. 21383967

2011
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.120 Biomarker BEFREE Confirmation of the roles of CTLA4 and PTPN22 as general immune function modulators with a nonlinear dose-response effect on autoimmunity, and confirmation of the role of IL2RA, which may act via a regulatory T cell subset on immune disease risk. 17989522

2007