Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 Biomarker BEFREE HLA-B27 but not NOD-2 was a predisposing factor for the inflammatory back disorders in IBD patients. 28961700

2018
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 Biomarker BEFREE The expression of miR-10a was markedly decreased, while NOD2 and interleukin (IL)-12/IL-23p40 were significantly increased, in the inflamed mucosa of IBD patients compared with those in healthy controls. 25281418

2015
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 Biomarker BEFREE IBD in patients with XIAP deficiency is similar to Crohn disease and is associated with defective NOD2 function in monocytes. 24942515

2014
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 GeneticVariation BEFREE IBD phenotype and NOD2 genotype were also selected as associated with shifts in the relative frequency of the C. coccoides--E. rectales group. 22719818

2012
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 GeneticVariation BEFREE The purpose of this study was to carry out a CARD15 sequence analysis in a large single-center IBD cohort and to investigate the impact of different genotypes on disease phenotypes. 17101573

2006
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 GeneticVariation BEFREE Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease--an IG-IBD study. 15654786

2005
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0022104
Disease: Irritable Bowel Syndrome
Irritable Bowel Syndrome 		0.070 GeneticVariation BEFREE The group of pedigrees that contained one of the three CARD15 variants had two suggestive linkage results occurring in 6p (lod = 3.06 at D6S197, IBD phenotype) and 10p (lod=2.29 at D10S197, CD phenotype). 13680363

2003