Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 Biomarker BEFREE SETD2 genetic polymorphism is associated with AML prognosis and chemotherapy outcome, suggesting the possibility for development in AML diagnostics and therapeutics towards SETD2. 30922329

2019
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 GeneticVariation BEFREE SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints. 30967619

2019
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 AlteredExpression BEFREE Prognostic significance of huntingtin interacting protein 1 expression on patients with acute myeloid leukemia. 28452374

2017
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 GeneticVariation UNIPROT Identification of functional cooperative mutations of SETD2 in human acute leukemia. 24509477

2014
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 Biomarker BEFREE Taken together, our results suggest that HIF-1α regulates the miRNA network to interfere with AML cell differentiation, representing a novel molecular mechanism for HIF-1-mediated anti-leukemic action. 23059786

2013
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 GeneticVariation BEFREE We screened 79 acute myeloid leukemia (AML) cell lines and found five positive for JAK2 V617F (HEL, MB-02, MUTZ-8, SET-2, UKE-1), 4/5 with histories of MPD/MDS. 16408098

2006
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.350 GeneticVariation UNIPROT Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1. 16314571

2005